ISSN 2149-5807 | E-ISSN 2149-6048
Original Article
The diagnostic value of Pentraxin-3 in patients with spontaneous subarachnoid and intracerebral haemorrhage
1 Department of Emergency Medicine, Karadeniz Technical University School of Medicine, Trabzon, Turkey  
2 Department of Emergency Medicine, Ordu University Training and Research Hospital, Ordu, Turkey  
3 Department of Emergency Medicine, Ankara Training and Research Hospital, Ankara, Turkey  
4 Department of Medical Biochemistry, Karadeniz Technical University School of Medicine, Trabzon, Turkey  
5 Program of Medical Laboratory Techniques, Vocational School of Health Sciences, Karadeniz Technical University, Trabzon, Turkey  
6 Department of Neurosurgery, Karadeniz Technical University School of Medicine, Trabzon, Turkey  
7 Department of Neurology, Karadeniz Technical University School of Medicine, Trabzon, Turkey  
Eurasian J Emerg Med ; : -
DOI: 10.5152/eajem.2017.70707
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Key Words: Spontaneous subarachnoid haemorrhage, intracerebral haemorrhage, pentraxin-3
Abstract

Aim: In this study, the diagnostic and prognostic values of serum Pentraxin3 (PTX3) level were evaluated in spontaneous subarachnoid haemorrhage (SAH) and intracerebral haemorrhage patients (ICH).


Materials and methods: The study was conducted prospectively between April 2014 and December 2015 in emergency department of Faculty of Medicine. Patients who were older than 18 years, who were presented to emergency department with neurologic findings, and who were diagnosed with SAH and ICH pursuant to CT scan of the brain. PTX3 levels were evaluated in the blood samples taken at the time of presentation to hospital and at 12th hour after presentation.


Results: In the study, the levels of serum PTX3 measured at presentation and at 12th hour after presentation were found to be statistically and significantly different in SAH group, in comparison to control group (p<0.001; p<0.001). The levels of serum PTX3 measured at presentation and at 12th hour after presentation were found to be significantly different in ICH group, in comparison to control group (p<0.001; p<0.001).


Conclusion: According to results of the study we have conducted, findings show that measuring the levels of serum PTX3 in SAH and ICH patients may be an adjuvant test. We consider that this finding should be supported by comprehensive and controlled studies.

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