ISSN 2149-5807 | E-ISSN 2149-6048
Original Article
Relationship of Serum Pentraxin-3 with Peripheral Arterial Disease
1 Department of Emergency Medicine, Ankara Training and Research Hospital, Ankara, Turkey  
2 Department of Emergency Medicine, Ordu University Training and Research Hospital, Ordu, Turkey  
3 Department of Nutrition and Dietetics, Karadeniz Technical University School of Health Sciences, Trabzon, Turkey  
4 Department of Emergency Medicine, Karadeniz Technical University School of Medicine, Trabzon, Turkey  
5 Program of Medical Laboratory Techniques, Karadeniz Technical University Vocational School of Health Sciences, Trabzon, Turkey  
6 Department of Cardiovascular Surgery, Ahi Evren Thoracic and Cardiovascular Surgery Training and Research Hospital, Trabzon, Turkey  
7 Department of Cardiovascular Surgery, Karadeniz Technical University School of Medicine, Trabzon, Turkey  
8 Department of Medical Biochemistry, Karadeniz Technical University School of Medicine, Trabzon, Turkey  
9 Public Hospitals Association Bakırköy General Secretaria, İstanbul  
10 Department of Emergency Medicine, Ufuk University School of Medicine, Dr. Rıdvan Ege Training and Research Hospital, Ankara, Turkey  
Eurasian J Emerg Med ; : -
DOI: 10.5152/eajem.2017.06977
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Key Words: Atherosclerosis, Inflammation, Pentraxin-3, Peripheral arterial disease
Abstract

Aim: Since atherosclerosis is a chronic inflammatory process associated with peripheral artery disease (PAD), the inflammatory marker pentraxin (PTX) may increase in PAD.

 

Materials and Methods: This cross-sectional clinical study was performed at the tertiary university hospital emergency department and cardiovascular surgery departments in Turkey. The purpose was to determine the value of PTX3 in the diagnosis of PAD. This study was performed on 43 symptomatic patients aged >18 years and diagnosed with PAD.

 

Results: Median PTX3 value was 1.027 (25–75th percentile: 0.395–2.902) in the control group and 0.585 (25–75th percentiles: 0.406–5.467) in the PAD group (p=0.913). A comparison of PTX3 with ankle brachial index (ABI) values revealed a weak and non-significant correlation (rho: 0.016, p=0.886). Analysis of PTX3 values with other parameters (age, systolic and diastolic blood pressure, heart rate, respiratory rate, temperature, and SpO2) revealed no significant correlation with any of the other parameters.

 

Conclusion: Our findings indicate that PTX3 levels cannot be used as a marker in patients with the chronic process of PAD.

 

 

Cite this article as: Katipoğlu B, Aygün A, Demir S, Tatlı Ö, Menteşe A, Menteşe Ü, et al. Relationship of Serum Pentraxin-3 with Peripheral Arterial Disease. Eurasian J Emerg Med 2017: DOI: 10.5152/eajem.2017.06977

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